Q: During which trimester is toxoplasmosis infection worse?

A: The risk and severity of the baby’s infection will depend partly on the timing of the mother’s infection — that is, whether she was infected in the first, second, or third trimester of pregnancy. If the mother first becomes infected in the third trimester, the fetus is more likely to become infected, but the severity in the fetus is less than if it becomes infected in the first trimester.