Among Jewish people there are certain genetic diseases occurring more frequently. There are nearly 4,000 genetic diseases known that afflict the world’s population. Certain genetic diseases occur at higher frequencies among certain ethnic, racial, or demographic groups.

Some disorders tend to be more common among Ashkenazi Jews because today's Ashkenazi Jews descended from a small group of founders. And for centuries, for political and religious reasons, Ashkenazi Jews were genetically isolated from the population at large.

Most Common Jewish Genetic Disorders:

• Bloom Syndrome
• Canavan Disease
• Crohn's Disease
• Cystic Fibrosis
• Dihydrolipoamide dehydrogenase deficiency
• Fabry Disease 
• Factor Xi Deficiency
• Familial Dysautonomia
• Familial Hyperinsulinism
• Familial Mediterranean Fever
• Fanconi Anemia
• Gaucher Disease
• Glycogen Storage disorder
• Joubert Syndrome
• Lipoamide Dehydrogenase deficiency 
• Machado Joseph Disease 
• Maple Syrup Urine disease
• Mucolipidosis IV
• Nemaline Myopathty
• Nieman-Pick
• Nonclassical adrenal hyperplasia
• Nonsymptomic hearing loss
• Spinal Muscular Atrophy (SMA)
• Tay-Sachs Disease
• Torsion Dystonia
• Usher Syndrome III
• Usher Syndrome IF
• Walker Warburg Syndrome

Genetic Predisposition

• Familial Colon Cancer
• Hereditary breast and ovarian cancer (BRCA1 and BRCA2)
• Ulcerative Colitis Crohn's Disease