Endocrine Disrupting Chemicals EDC Pesticides and Pregnancy
Pregnancy Safety
Obie Editorial Team
Endocrine-disrupting chemicals (EDC) are synthetic chemicals that when absorbed into the body either mimic or block hormones and disrupt the body's normal functions. This disruption can happen through altering normal hormone levels, halting or stimulating the production of hormones, or changing the way hormones travel through the body, thus affecting the functions that these hormones control.
Chemicals that are known human endocrine disruptors include:
Many chemicals, particularly pesticides and plasticizers, are suspected endocrine disruptors based on limited animal studies.
In the 1950s and 1960s, pregnant women were prescribed diethylstilbestrol (DES), a synthetic estrogen, to prevent miscarriages. Not only did DES fail to prevent miscarriages, but it also caused health problems for many of these women's children. In 1971, doctors began reporting high rates of unusual vaginal cancers in teenage girls. Investigations of the girls' environmental exposures traced the problem to their mothers' use of DES. The girls also suffered birth defects of the uterus and ovaries and immune system suppression.
Because endocrine disruptors affect the development of the body's vital organs and hormonal systems, infants, children, and developing fetuses are more vulnerable to exposure. And as was the case with DES, parents' exposure to certain chemicals may produce unexpected -- and tragic -- effects in their children, even decades later.
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